RNAi Technology Notes - Search localsearch

wikipedia.org

https://en.wikipedia.org/wiki/RNA_interference

RNAi has an important role in defending cells against parasitic nucleotide sequences (e.g., viruses or transposons) and also influences development of organisms. The RNAi pathway is a naturally occurring process found in many eukaryotes.

britannica.com

https://www.britannica.com/science/RNA-interferenc…

RNA interference | Explanation, Function, & Examples | Britannica

RNA interference (RNAi), regulatory system occurring within eukaryotic cells (cells with a clearly defined nucleus) that controls the activity of genes. RNAi functions specifically to silence, or deactivate, genes.

umassmed.edu

https://www.umassmed.edu/rti/biology/rna/how-rnai-…

What is RNAi - RNAi Biology | UMass Chan Medical School

The term RNA interference (RNAi), discovered by the RTI's Craig Mello and Stanford's Andrew Fire who won the Nobel prize for this discovery in 2006, was coined to describe a cellular mechanism that use the gene's own DNA sequence to turn it off, a process that researchers call silencing.

nih.gov

https://pmc.ncbi.nlm.nih.gov/articles/PMC309050/

RNA Interference: Biology, Mechanism, and Applications - PMC

Double-stranded RNA-mediated interference (RNAi) is a simple and rapid method of silencing gene expression in a range of organisms. The silencing of a gene is a consequence of degradation of RNA into short RNAs that activate ribonucleases to target homologous mRNA.

nature.com

https://www.nature.com/articles/s41587-023-02105-y

RNA interference in the era of nucleic acid therapeutics

Two decades of research on RNA interference (RNAi) have transformed a breakthrough discovery in biology into a robust platform for a new class of medicines that modulate mRNA expression.

the-scientist.com

https://www.the-scientist.com/gene-silencing-with-…

What Is RNAi? Gene Silencing Explained for Researchers and Innovators

Learn what RNAi is and how RNA interference enables precise gene silencing for research, agriculture, and therapeutic use. Using small interfering RNA or microRNA that are complementary to a target sequence, scientists can direct the RNA interference (RNAi) pathway to silence genes of interest.

abcam.com

https://www.abcam.com/en-us/knowledge-center/dna-a…

RNA interference: Mechanism and applications | Abcam

RNA interference (RNAi) is a biological process in which RNA molecules are involved in sequence-specific suppression of gene expression using double-stranded, small RNAs. RNAi typically leads to gene knockdown, reducing expression levels rather than eliminating them through silencing.

thermofisher.com

https://www.thermofisher.com/us/en/home/life-scien…

RNA Interference (RNAi) - Thermo Fisher Scientific - US

RNA interference (RNAi) is a highly conserved biological process in which RNA molecules target mRNA transcripts to cause specific gene silencing. This pathway is a crucial part of cellular defense and is also involved in regulating various physiological processes.

alnylam.com

https://www.alnylam.com/our-science/the-science-of…

How RNAi Works | Alnylam® Pharmaceuticals

RNA interference (RNAi) is a natural biological process that regulates gene expression (how your body makes proteins) by "interfering" with messenger RNA (mRNA) which carry DNA's instructions for making new proteins.

sciencedirect.com

https://www.sciencedirect.com/topics/biochemistry-…

RNAI - an overview | ScienceDirect Topics

RNA interference (RNAi) is defined as a natural mechanism where double-stranded RNA molecules induce sequence-specific degradation of target RNA, primarily through the action of short interfering RNA (siRNA) and the RNA-induced silencing complex (RISC).