Gene expression is controlled, in part, by the interactions between genes and regulatory elements located along the genome.

In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be helpful for learners to begin with the linear presentation of how ...

A novel, freely available AI tool has cut the time it takes to determine chromatin structure from days to minutes. The 3D structure of DNA is important for controlling cell-specific gene expression ...

Penn Engineers have developed a new way to use AI to solve inverse partial differential equations (PDEs), a particularly ...

Every cell in a body contains the same genetic sequence, yet each cell expresses only a subset of those genes. These cell-specific gene expression patterns, which ensure that a brain cell is different ...

From memory formation to disease prevention, scientists are uncovering how chromatin structure, enzyme evolution, and epigenetic regulators orchestrate gene activity. Recent breakthroughs reveal how ...

Researchers use AI to discover 14 distinct nucleosome states, revealing that DNA packaging acts as a "volume dial" for gene ...

Using an AI-driven approach, researchers found DNA within nucleosomes is often partly exposed, enabling nuanced gene ...

A recent study has shed light on the transcriptional regulatory mechanisms of Penicillium expansum, the fungal culprit behind blue mold disease in fruits. By mapping chromatin accessibility at ...