Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

A Northwestern Medicine study has revealed a previously unknown connection between two fundamental cellular processes, ...

The SWI/SNF Ig-Fold for Transcription Factor Interactions or 'SWIFT' domain on mSWI/SNF chromatin remodeling complexes engage ...

Chromatin remodelers are ATP-dependent motor proteins that dynamically reorganize chromatin architecture, playing essential roles in gene expression, development, and immune function. Dysregulation of ...

Cells depend on the precise reading of DNA sequences to function correctly. This process, known as gene expression, determines which genetic instructions are activated. When this fails, the wrong ...

A new study by Dr. Tian Ye's group from the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences (CAS) has revealed that mitochondrial stress coordinates chromatin ...