Proteomics Approaches to Analysis of the Cytoskeleton in Immune Cells Cytoskeletal proteins are often identified in many proteomic studies either as contaminants, owing to their very high abundance, ...

The cytoplasm of eukaryotic cells contains an elaborate filamentous protein meshwork — the cytoskeleton — which comprises three distinct but integrated fibrous polymers: filamentous actin (F-actin; ...

The study of pathways that trigger apoptosis and ageing is crucial for increasing our understanding of these fundamental processes. Whereas apoptosis is probably triggered by a range of both ...

Robert Mauck, PhD, from the University of Pennsylvania, discussed how aging and differentiation alter nuclear mechanobiology at the 2014 American Society of Bone and Mineral Research Conference in ...

Techniques such as RNA interference suppression and disruption of CBP–cytoskeleton interaction by site-directed mutagenesis should be carried out in order to investigate the significance of newly ...