New Cornell research is providing a fresh view into the ways a common chemotherapy agent, etoposide, stalls and poisons the essential enzymes that allow cancer cells to flourish. The findings, from ...
Andrés Aguilera's laboratory, in collaboration with that of Ralf Wellinger (both professors in the Department of Genetics at the University of Seville in CABIMER) and with PharmaMAR, has identified ...
New research is providing a fresh view into the ways a common chemotherapy agent, etoposide, stalls and poisons the essential enzymes that allow cancer cells to flourish. New Cornell research is ...
Bacterial topoisomerase inhibitors represent a promising class of antimicrobial agents that target essential enzymes involved in DNA replication and maintenance. By inhibiting enzymes such as DNA ...
New research published in Nature Communications has linked a normal cellular process to an accumulation of DNA mutations in ...
The solution to DNA's topological problems comes in the form of enzymes called topoisomerases that serve as "swivels" and allow the molecule to perform its requisite acrobatics. Type I topoisomerase ...
An entirely new approach to inhibiting DNA-cleaving enzymes works through the aggregation of an otherwise non-toxic molecule. This discovery may lead to a much-needed method for curbing Streptococcus ...
A Dutch led international team of researchers has unravelled how nature releases the torque built up in DNA at the molecular level. The researchers from Delft University of Technology, the Ecole ...
Today (September 19), the Lasker Foundation announced this year’s winners of the Lasker Awards. Zhijian “James” Chen, a biochemist at the University of Texas Southwestern Medical Center, was awarded ...
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