When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

Researchers have identified an alternate method to study changes during the DNA replication process in lab settings using genetically modified yeast. The new approach offers a clearer window than ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

Researchers have identified the mechanism used by the helicase ring to thread around and separate entwined DNA strands in the replication process. DNA replication is a complex process in which a ...

Unlike nuclear DNA, mitochondrial DNA (mtDNA) is circular in nature and organized as mitochondrial nucleoids comprised of DNA-protein complexes that are distributed in the matrix. It is also inherited ...

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...