Mapping transcription factor (TF) binding sites across the genome is key to understanding how cells control gene expression, yet pinpointing their footprints across the genome—especially in single ...
DNA binding specificities of transcription factors (TFs) are a key component of gene regulatory processes. Underlying mechanisms that explain the highly specific binding of TFs to their genomic target ...
In biology classrooms, we often learn that genes are transcribed into mRNA, which is then translated into proteins—a tidy, linear process. But gene expression in living cells is far more intricate, ...
During development, transcription factors (TF) control cell fate decisions by binding to DNA “enhancer” sequences to drive gene expression. However, the mechanism by which TFs contend with the ...
Marligen Biosciences’ (www.marligen.com) multiplex transcription factor profiling tools have been successfully used to address a variety of problems inherent in drug discovery and development.
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