Solving the structure of an amyloid protein gives new insight into limb-girdle muscular dystrophy type 3 (LGMD D3) and functional protein aggregation. LGMD D3 is a rare disease characterized by slow ...
Limb-girdle muscular dystrophy type 3 (LGMD D3) is a rare disease causing progressive muscle weakness, caused by point mutations in the hnRNPDL-2 protein. A member of the RNA-associated ...
Toward the goal of efficient editing of farm animals for genetic improvements, this study explores an upgraded form of nuclease PE (uPEn). Based on the resolved structure of the NiV polymerase L-P ...