How an enzyme activates its substrate for turnover is fundamental for catalysis but incompletely understood on a structural level. With redox enzymes one typically analyses structures of ...

To be used industrially, enzymes usually need to undergo some surgery before they can become chemical workhorses. It may take a nip here, or a tuck there, to sculpt their active site into a shape that ...

Scott Nelson, left, and Nathaniel Kallmyer work in the laboratory of Zymosense, a startup company based in the Iowa State ...

Researchers want to transform the natural and abundant resource wood into useful materials, and central to that is a molecular machine found in fungi that decomposes the complex raw material into its ...

High-resolution structures explain the mechanism of human PNPase and provide insights into mutations causing hereditary ...

Chemists at MIT have introduced an engineered biosynthetic enzyme that accepts a wider range of substrates into periwinkle plant culture to make unnatural analogs of alkaloids (Nat. Chem. Biol., DOI: ...

The mechanism by which an enzyme used in industrial production of an important drug for type-2 diabetes recognizes its target has been demonstrated by a group of researchers. This finding will further ...

Enzymes are essential for life and are one of the most important types of protein in the human body. Studying enzyme kinetics provides information about the diverse range of reactions in the human ...

CHAPEL HILL, N.C. – Cancer spreads throughout the human body in cunning, almost militaristic, ways. For example, it can manipulate our genetic make-up, take over specific cell-to-cell signaling ...

Enzymes are biological catalysts that speed up chemical reactions in living organisms. They are essential for life, as they play a crucial role in various biological processes, such as digestion, ...

Enzyme kinetics involves the measurement of the rate at which chemical reactions that are catalyzed by enzymes occur. Knowledge about the kinetics of an enzyme can reveal useful information about its ...