A novel electrode platform detects dopamine from single living brain organoids in real time, enabling non-destructive ...

Neuronal calcium sensors (NCS) comprise a pivotal family of EF‐hand calcium‐binding proteins that translate transient fluctuations in intracellular Ca²⁺ into specific cellular responses. These ...

An interactive toolbox for standardizing, validating, simulating, reducing, and exploring detailed biophysical models that can be used to reveal how morpho-electric properties map to dendritic and ...

Brain functions stem from and rely on electrical signals created and propagated by neurons. As such, scientists measure electrical signals to study neuronal function at both single-cell and systemic ...

A team of researchers from the University of Massachusetts Amherst is the first to show how proteins called "chaperones" are vital in ensuring that neurons can transmit signals to one another. When ...

When triggered by an odor, rapid changes in membrane voltage and intracellular calcium ion levels occur in nematode olfactory neurons, causing membrane voltage sensors and calcium ion sensors to ...

In many ways, the brain is uncharted territory akin to the deepest parts of the ocean and farthest reaches of outer space. As with any new frontier, navigating it requires a map. Researchers have ...

A clearance mechanism involving microglia has been known to relieve neurons of toxic protein aggregates such as those associated with Alzheimer’s disease and Parkinson’s disease. Unfortunately, this ...

Every movement you make and every memory you form depends on precise communication between neurons. When that communication ...

Nerve fibers in the brain and spinal cord are wrapped in an insulating sheath known as myelin. For a long time, this barrier, ...

Fluctuations in brain activity, also known as neural variability, enable us to be flexible in adjusting our behavior to the current situation. A new study shows that neural variability increases ...