News Medical

Polymorphisms in human immunoglobulin heavy chain genes can influence the function of SARS-CoV-2 neutralizing antibodies

In a recent study published in Immunity, researchers isolated SARS-CoV-2 spike (S) protein-targeted mAbs (monoclonal antibodies) from convalescent healthcare workers (HCWs), emphasizing the IGHV1-69 ...
Nature

Polymorphisms at codons 56 and 174 of the prion-like protein gene (PRND) are not associated with sporadic Creutzfeldt-Jakob disease

Human prion diseases are neurodegenerative disorders characterized by the accumulation of an abnormal protease-resistant isoform of the prion protein PrP Sc (Prusiner 1996). The prion-like protein ...
JSTOR Daily

Evolution of the Human ABO Polymorphism by Two Complementary Selective Pressures

The best-known example of terminal-glycan variation is the ABO histo-blood group polymorphism in humans. We model two selective forces acting on histo-blood group antigens that may account for this ...
JSTOR Daily

Genetic Studies of Human Apolipoproteins: XIII. Quantitative Polymorphism of Apolipoprotein C-III in the Mayans of the Yucatán Peninsula

This is a preview. Log in through your library . Abstract Apolipoprotein C-III (APO C-III) is a structural component of very-lowdensity and high-density lipoprotein particles and is an inhibitor of ...
EurekAlert!

Scientists construct human genome microsatellite polymorphism map

A research team led by Profs. XU Tao and HE Shunmin from the Institute of Biophysics of the Chinese Academy of Sciences has recently constructed a global polymorphism genetic map of variable number ...