Purdue University researchers have taken the first steps to treat Alzheimer’s disease, Parkinson’s disease and Type 2 diabetes by creating multiple patent-pending compounds shown to inhibit protein ...

Proteins are made of chains of amino acids, and a basic tenet of biology is that the sequence of amino acids determines how a protein folds into a 3D shape which, in turn, dictates the protein’s ...

Proteins are essential for numerous physiological processes, serving roles as diverse as cellular building blocks, hormones, enzymes for metabolic reactions, and antibodies that support immune defense ...

Textbooks often depict proteins in one conformation, but real life, as usual, is much messier. While some proteins have stable, unchanging structures, many others have intrinsically disordered regions ...

The accumulation of misfolded proteins in the brain is central to the progression of neurodegenerative diseases like Huntington's, Alzheimer's and Parkinson's. But to the human eye, proteins that are ...

Protein aggregation is typical of various neurodegenerative diseases such as Alzheimer's, Parkinson's and prion diseases such as Creutzfeld-Jakob disease. A research team has now used new in vitro and ...

Examining an intrinsically disordered protein: "Re" is the end-to-end distance or height, "Rg" is the radius of gyration or overall size. Proteins are essential for our human body functions. There are ...

Inside each cell of the human body are proteins that control which genes are expressed at the right place and time. However, intriguingly, many of the most important proteins involved in gene ...

Researchers of Mainz University and EMBL Hamburg present a new approach to determine the form of disordered proteins by using two different methods simultaneously in a single sample. Proteins are ...

Durable analytical instruments expedite the study of misfolded proteins linked to neurodegenerative diseases. To overcome these limitations, scientists developed the real-time quaking-induced ...