In Greek mythology, Proteus, son of Poseidon and prophetic shepherd of sea-beasts, could foretell the future. The elusive sea god was difficult to capture as he assumed many forms—a lion, a serpent, ...
Inside each cell of the human body are proteins that control which genes are expressed at the right place and time. However, intriguingly, many of the most important proteins involved in gene ...
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Order from disordered proteins: Physics-based algorithm designs biomolecules with custom properties
In synthetic and structural biology, advances in artificial intelligence have led to an explosion of designing new proteins with specific functions, from antibodies to blood clotting agents, by using ...
Jane Richardson never considered herself an artist. Then, in the late 1970s, the structural biologist found herself in need of some colored pencils, pastels and sketching paper. Richardson, a ...
Researchers at Harvard and Northwestern have developed a machine learning method that can design intrinsically disordered proteins with custom properties, addressing nearly 30% of all human proteins ...
For decades, scientists have relied on structure to understand protein function. Tools like AlphaFold have revolutionized how researchers predict and design folded proteins, allowing for new ...
A milestone in biology has been achieved thanks to artificial intelligence (AI) machine learning and applied physics. A new peer-reviewed study by researchers affiliated with Harvard John A. Paulson ...
Proteins are most well-known for their intricate structures. The α-helices and β-sheets that form from interactions between sidechains create distinct shapes that, along with the specific amino acid ...
(MEMPHIS, Tenn. – December 3, 2025) Fusion oncoproteins arise when a gene fuses with another gene and acquires new abilities. Such abilities can include the formation of biomolecular condensates, ...
Intrinsically disordered proteins (IDPs) make up about 30 percent of our proteome. They are important to many fundamental aspects of biology and disrupted in disease. Since they lack a stable shape, ...
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