LAG-3 exerts its inhibitory function by undergoing phase separation with the CD3ε subunit of the TCR/CD3 complex; Enhancing the cis-proximity between LAG-3 and TCR through a LAG-3/TCR bispecific ...
Immune checkpoint pathways regulate T cell function and play pivotal roles in the treatment of both cancer and autoimmune diseases. One key component of these pathways is Lymphocyte Activation Gene 3 ...
CD3 (including its subunits CD3ε, CD3δ, CD3γ, and CD3ζ) is the central component of the TCR-CD3 complex and is crucial for recognizing T cells and responding to antigens. Every subunit of CD3 has ...
Hosted on MSN
Overlooked cells go on the offensive: Researchers discover antitumor potential of CD4 T lymphocytes
In the fight against cancer, immunotherapy—which aims to boost the body's natural defenses against cancer—is experiencing remarkable growth. Most of these treatments are based on CD8 T lymphocytes, ...
Hope for adults and children with cancers Camilla Jandus' team is currently preparing a clinical trial of TCR-engineered CD4-based cell therapy. The trial will include different types of cancer ...
Planegg/Martinsried, December 9, 2024.Medigene AG (Medigene or the “Company”, FSE: MDG1, Prime Standard), an oncology platform company focused on the research and development of T cell receptor ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback