To better understand how RNA in bacteria gives rise to protein--and along the way, target these processes in the design of new antibiotics--researchers are turning their attention to the unique way ...

Single-molecule multi-colour fluorescence microscopy allowed the Duss Group at EMBL Heidelberg to capture a movie showing interactions between bacterial RNA polymerase (labelled with the pink sphere) ...

Choosing a film for a movie night is always a battle. Now imagine if you could pick one that provided a window into some of the most fundamental biological processes that keep us alive. For the first ...

Native cell-free transcription–translation systems offer a rapid route to characterize the regulatory elements (promoters, transcription factors) for gene expression from nonmodel microbial hosts, ...

Heme binding to a bacterial transcription factor is critical for hydrogen sulfide (H 2 S) signaling, report researchers from Japan. Heme binding promotes the reaction of H 2 S with the transcription ...

Three new studies provide structural clues about how ribosomes and RNA polymerase are coupled to one another during bacterial gene expression. Both teams found that when the mRNA spacer between RNA ...