This article was originally published on www.fansided.com as NFL Week 15 picks and predictions, straight-up and ATS: Bills-Patriots, Packers-Broncos lead huge slate.

Frank analyzes which defenses (DEF) to sit or start in Week 16 (2025), and provides his best fantasy football playoffs D/ST streaming options and schedules.

In Sporting News' Week 12 picks and predictions, Los Angeles delivers a blow to Detroit's playoff hopes, while Buffalo splits an important AFC East series.

No. 2 Packers 24-17 over No. 7 Bears. These two teams met in Week 14, and although it was a close game, the Packers felt like the better team. Jordan Love outplayed Caleb Williams, and if we get a rematch in the playoffs, that feels like a scenario we'd see once again.

That recent stretch of success, as well as the fact that they are playing the Jets on Sunday, should make the Dolphins an attractive pick this week. Especially if you're looking ahead and potentially trying to save teams like Philadelphia (vs. Las Vegas) and Buffalo (vs. Cleveland) in future weeks.

Netflix will broadcast two Christmas Day matchups on Thursday, Dec. 25: Cowboys vs. Commanders (1 p.m. ET) and Lions vs. Vikings (4 p.m. ET). Prime Video will broadcast the Christmas nightcap between the Broncos and Chiefs (8:15 p.m. ET).

Are there some leftovers that you've been waiting to break out until Sunday's Week 13 action in the NFL? We're right there with you. As we sit back, relax, and wrap up the bulk of this week's action in the NFL,