AZoLifeSciences on MSN
Researchers capture the most detailed images of molecules in chromatin condensates
A team of researchers led by HHMI Investigator Michael Rosen has captured the most detailed images yet of the molecules in ...
Researchers discovered that stiff DNA segments inside nucleosomes physically block chromatin remodeling. The remodeling machinery normally shifts DNA by creating 20–30 base-pair loops, but these ...
The nuclei of most human cells contains the entire genome, which would have a length of about six feet if it was fully extended. So this DNA has to be carefully compacted in cells, while still ...
Morning Overview on MSN
Microscopic droplets reveal DNA’s hidden architecture
Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to ...
A team led by HHMI Investigator Michael Rosen used advanced imaging techniques to understand how fibers of compacted DNA and proteins are organized and interact inside membrane-less, droplet-like ...
A single cell contains 2-3 meters of DNA, meaning that the only way to store it is to package it into tight coils. The solution is chromatin: a complex of DNA wrapped around proteins called histones.
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