Recently identified and long-lasting type of protein misfolding — non-native entanglements — observed in all-atom protein folding simulations. Representative misfolded conformations of the small ...
LA JOLLA, CA – July 12, 2012 –Readers of the top-ranked scientific journals Science and Nature might have noticed a recent wave of articles, most recently in the July 13, 2012 issue of Science, with ...
Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified a small molecule that can inhibit a cancer ...
We may have been overestimating the role of a pathological class of misfolded protein in neurodegenerative disease.
Chemobiological screening for identification of molecular targets for thymic epithelial cancers. Background: The importance of definitive histologic subclassification has significantly increased as ...
A research group has found a new class of proteins in the red algae Cyanidioschyzon merolae that are involved in moving proteins across the membranes of chloroplasts -- subcompartments that conduct ...
WALTHAM, Mass.--(BUSINESS WIRE)--Avilar Therapeutics, a biopharmaceutical company focused on extracellular protein degradation, today announced a scientific poster presentation highlighting ATACs ...
Molecular glues are revolutionizing cancer therapy by targeting undruggable proteins for degradation, enhancing precision ...
Research by University of California (UC), San Diego, School of Medicine scientists has demonstrated how RNA-binding proteins may represent a new class of drug target for cancers, including ...