Recently, a collaborated research group from Hefei Institutes of Physical Science (HFIPS) of Chinese Academy of Sciences (CAS) and The Second Hospital of Anhui Medical University dissected, for the ...
This is a preview. Log in through your library . Abstract To elucidate the role of the mismatch repair gene Mlh1 in genome instability during the fetal stage, spontaneous mutations were studied in ...
PATIENTS AND METHODS: Clinical and pathologic data were collected from 138 families with HNPCC. Mutation analyses were performed for all families. Survival analysis was used to calculate the ...
Prediction models that incorporate certain personal and family medical history characteristics can help identify high-risk patients who are likely to have a gene mutation associated with a type of ...
After learning that I had Lynch syndrome and a MLH1 mutation, I changed my lifestyle to hopefully prevent a cancer diagnosis. After meeting with a genetic counselor, undergoing genetic testing for ...
Patients with DNA mismatch repair deficiency rectal cancer may not necessarily have Lynch syndrome. Expert Yi-Qian Nancy You weighs in on the topic. It is important to have a well-rounded ...
Dear Dr. Roach: I am a healthy 55-year-old woman who eats well and exercises (with both weights and cardio) six to seven times per week. Four years ago, I was diagnosed with Lynch syndrome. (I have ...
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