RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function ...

Researchers at Arizona State University’s (ASU) School of Molecular Sciences and the Biodesign Institute’s Center for the Mechanism of Evolution have discovered an unprecedented pathway producing ...

A study captured the first near frame-by-frame view of a self-splicing ribozyme assembling into its active form. Using ...

This article explores how challenges such as sequence optimization, immune activation and off-target effects are being ...

Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have captured the first detailed molecular snapshots of human polynucleotide phosphorylase (hPNPase) in action, ...

RNA in cells performs an astounding number of functions. Messenger RNA carries the sequences of active genes to cellular machinery that turns it into proteins. And transfer RNA molecules are an ...

The central dogma of molecular biology showing what is happening in this study. Credit: Julian Chen For the very first time, a study led by Julian Chen and his group in Arizona State University's ...

Researchers have used cryo-EM and computational tools to visualize ribozyme assembly, shedding light on life's most versatile ...

The discovery of a juvenile woolly mammoth named Yuka, found in Siberian permafrost with its skin and muscles intact, has already marked paleontological history. A team of scientists has just ...

Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified a small molecule that can inhibit a cancer ...