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  1. Melatonin: What It Is, What It Does & How It Works - Cleveland Clinic

    Apr 28, 2025 · Melatonin is a natural hormone that’s mainly produced by your pineal gland in your brain. It plays a role in managing your sleep-wake cycle and circadian rhythm.

  2. Melatonin: Benefits, Uses, Side Effects and Dosage - Healthline

    Feb 25, 2025 · Melatonin is often called the sleep hormone — and for good reason. It’s one of the most popular sleep aids and a common natural remedy to treat issues like insomnia. Multiple studies have...

  3. Melatonin: Overview, Uses, Side Effects, Precautions ... - WebMD

    It regulates night and day cycles or sleep-wake cycles. Melatonin in supplements is usually made in a lab. Darkness triggers the body to make more melatonin, which signals the body to sleep.

  4. Melatonin - Mayo Clinic

    Aug 13, 2025 · Melatonin is a hormone in your body that plays a role in sleep. The production and release of melatonin in the brain is connected to time of day, increasing when it's dark and …

  5. Melatonin: Side Effects & Dosage Guide for Sleep - Drugs.com

    Jun 25, 2025 · Learn what melatonin is, how it helps with sleep, recommended adult and child doses, common side effects, and long-term safety considerations.

  6. Melatonin: What You Need To Know | NCCIH

    What is melatonin and how does it work? Melatonin is a hormone that your brain produces in response to darkness. It helps with the timing of your circadian rhythms (24-hour internal clock) and with sleep. …

  7. Melatonin - Wikipedia

    Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [1] . Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the …

  8. Melatonin and your sleep: Is it safe, what are the side effects and how ...

    Feb 5, 2025 · Melatonin supplements are increasing in popularity. But how does melatonin help you sleep, and how often should you take it? Learn more about this sleep aid, whether it's safe for kids, …

  9. Melatonin: Usage, Side Effects, and Safety - Sleep Foundation

    Jul 10, 2025 · Melatonin is a hormone that regulates the sleep-wake cycle. Supplementary melatonin can help you fall asleep or adjust to new time zones. Experts recommend a dosage of 1 to 5 …

  10. Long-term use of melatonin supplements to support sleep may have ...

    Nov 3, 2025 · Melatonin supplements are promoted and marketed as a safe sleep aid; however, data demonstrating their long-term cardiovascular safety are lacking, which prompted the researchers to …