Aug 4, 2014 · Vortioxetine received FDA approval for the treatment of major depressive disorder in 2013. The drug is an SSRI, but it also acts as a 5HT agonist, antagonist, and transport inhibitor. 3

Mar 3, 2020 · Vortioxetine is an effective and safe switch therapy for treating selective serotonin reuptake inhibitor (SSRI)-induced sexual dysfunction in adults with well-treated major depressive …

PATIENT FACT SHEET Antidepressants and Weight Gain: What Patients Need to Know

Sep 20, 2024 · For patients and clinicians concerned about antidepressants and weight gain, our patient fact sheet provides helpful guidance.

Jul 2, 2020 · Sexual dysfunction has a significant impact on quality of life, personal relationships, self-esteem, and recovery, and it is a common cause for nonadherence or discontinuation of medication.

Oct 23, 2018 · Takeda announced that the FDA has approved a labeling update for Trintellix to include new head-to-head clinical data comparing it to Lexapro for improving treatment-emergent sexual …

Jan 19, 2018 · Vortioxetine was more efficacious in people with generalized anxiety disorder who had higher levels of pre-treatment functioning.

Aug 25, 2025 · People stopping antidepressants experienced more discontinuation symptoms, though this number was still less than the clinically significant cutoff.

Jun 7, 2019 · Findings of the study revealed that the frequency of adverse events compared with placebo was statistically similar in patients receiving SSRIs but was higher in patients taking SNRIs.

Oct 25, 2019 · Researchers found data that showed the Work Limitations Questionnaire is a useful tool to identify working patients with major depressive disorder and cognitive impairment.