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  1. Vortioxetine: A Unique Antidepressant for Major Depressive Disorder

    Aug 4, 2014 · Vortioxetine received FDA approval for the treatment of major depressive disorder in 2013. The drug is an SSRI, but it also acts as a 5HT agonist, antagonist, and transport …

  2. Can Vortioxetine Ameliorate SSRI-Induced Sexual Dysfunction in …

    Mar 3, 2020 · Vortioxetine is an effective and safe switch therapy for treating selective serotonin reuptake inhibitor (SSRI)-induced sexual dysfunction in adults with well-treated major …

  3. PATIENT FACT SHEET Antidepressants and Weight Gain: What Patients Need to Know

  4. Antidepressants and Weight Gain: What Patients Need to Know

    Sep 20, 2024 · For patients and clinicians concerned about antidepressants and weight gain, our patient fact sheet provides helpful guidance.

  5. Managing Antidepressant-Induced Sexual Dysfunction

    Jul 2, 2020 · Sexual dysfunction has a significant impact on quality of life, personal relationships, self-esteem, and recovery, and it is a common cause for nonadherence or discontinuation of …

  6. Vortioxetine Beats Escitalopram in Improving SSRI-Induced Sexual ...

    Oct 23, 2018 · Takeda announced that the FDA has approved a labeling update for Trintellix to include new head-to-head clinical data comparing it to Lexapro for improving treatment …

  7. Pretreatment Functioning Associated With Anxiolytic Efficacy of ...

    Jan 19, 2018 · Vortioxetine was more efficacious in people with generalized anxiety disorder who had higher levels of pre-treatment functioning.

  8. Patients Discontinuing Antidepressants Do Not Have …

    Aug 25, 2025 · People stopping antidepressants experienced more discontinuation symptoms, though this number was still less than the clinically significant cutoff.

  9. Treating MDD in Older Patients: Adverse Effects of Drug Therapy ...

    Jun 7, 2019 · Findings of the study revealed that the frequency of adverse events compared with placebo was statistically similar in patients receiving SSRIs but was higher in patients taking …

  10. Major Depressive Disorder and Improving Cognitive Functioning

    Oct 25, 2019 · Researchers found data that showed the Work Limitations Questionnaire is a useful tool to identify working patients with major depressive disorder and cognitive impairment.