Angioedema is swelling in the tissue under your skin. It’s most common in your lips, eyelids, tongue, genitals, hands and feet. Causes include allergies, medication side effects, vibrations, inherited gene …

What causes angioedema? Angioedema is caused by an increase in local capillary permeability and plasma extravasation, usually mediated by mast cells, histamine, or bradykinin release.

Sep 4, 2025 · The pathogenesis and causes of angioedema will be reviewed here. The clinical features, diagnosis, differential diagnosis, and management of acute angioedema are discussed separately.

Sep 20, 2025 · A vicious-spiral physiology explains why people who are predisposed to develop angioedema (e.g., hereditary angioedema) may be fine for long periods of time and then suddenly …

Jul 21, 2023 · Allergic and drug-induced angioedema usually happen within an hour of exposure to your trigger. Hereditary and acquired types usually happen over many hours, but it can feel much faster if …

Sep 11, 2025 · Angioedema is the swelling under the skin caused by allergies, infections, or genetics. Angioedema can cause breathing problems and might need emergency treatment if it affects the throat.

Oct 27, 2023 · Angioedema can arise with hives or alone. It causes swelling in the deeper layers of skin, often around the face and lips. Short-lived (acute) hives and angioedema are common. Most times, …

Mar 31, 2024 · Angioedema may occur alone or with other illnesses (including autoimmune disorders such as lupus, leukemia, and lymphoma). A rare form of angioedema runs in families and has …

Angioedema is edema of the deep dermis and subcutaneous tissues. It is usually acute but sometimes is a chronic mast cell–mediated reaction caused by exposure to a medication (eg, angiotensin …

This pathway involves the release of bradykinin, a molecule that acts on blood vessels and causes fluid leakage into the surrounding tissues. The causes of bradykinin-mediated angioedema are usually …